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Ovulation Induction or Superovulation

What Is Ovulation Induction?

The focus of ovulation induction therapy is to achieve healthy ovulation and, depending on the diagnosis, the ovulation of multiple eggs instead of just one each month. Inducing the release of more than one egg within intrauterine insemination (IUI) can dramatically increase a woman’s per cycle chance of pregnancy.

How Ovulation Induction Therapy Works

1. The first step in superovulation therapy is to administer medications to enhance the development of a mature egg(s) by the ovaries. 

2. The development of the eggs in their follicles (fluid-filled sacs) in the ovary is then monitored by transvaginal ultrasound.

3. Once the follicles have reached the appropriate size to contain a mature egg, an injection is given to trigger ovulation.

4. Patients then have scheduled sexual relations over the next two days to coincide with ovulation. If, instead, the treatment plan requires intrauterine insemination, it is performed during the same two days. 

5. A simple blood test done five to seven days later confirms whether your hormone levels are appropriate. If necessary, your fertility specialist will prescribe hormonal supplementation.

The goal of ovulation induction is to ensure that ovulation will occur at the same time that the sperm will reach the egg(s).  This increases the likelihood that fertilization will occur and hopefully result in a pregnancy.

ovulation induction fertility treatment

Medications Used for Ovulation Induction

  • Clomiphene citrate (Clomid® or Serophene®)
  • Gonadotropinsare medications that are injected using a very small needle. These medications, which are used to stimulate follicle development, are known by the following trade names:
    • Gonal-F®
    • Follistim®
    • Bravelle®
    • Menopur® 

Medications Used to Induce Ovulation (Egg Release)

Your body naturally releases another substance called luteinizing hormone (LH) to trigger egg release. There are two additional medications we use to do this at the best time in your ovulation induction cycle:

  • hCG (human chorionic gonadotropin) is an ovulation medicine given by injection which can be used to trigger egg release. Commercial brands are known as:
    • Pregnyl®
    • Novarel®
  • Ovidrel®

Contact us for more information about ovulation medicine for ovulation induction or superovulation.

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