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ICSI – A Possible Solution for Male Factor Infertility Blog Feature
Lisa Rosenthal

By: Lisa Rosenthal on August 23rd, 2016

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ICSI – A Possible Solution for Male Factor Infertility

Male Infertility | Fertility Treatment | In Vitro Fertilization (IVF)

ICSI & IVF for male factor infertilityMale factor infertility accounts for about 40% of trouble in conceiving. Read below for one of the most reliable and significant ways that a reproductive endocrinologist can work with a male factor problem.

Treating Male Factor Infertility with ICSI and IVF

Intracytoplasmic Sperm Injection (ICSI) is a process of micromanipulation that is used to treat severe forms of male infertility.

With this technique, the embryologist injects a single sperm into the center of each egg retrieved as part of the in vitro fertilization (IVF) cycle. The sperm may be either 'washed' or 'unwashed' for the intracytoplasmic sperm injection.The fertilized egg grows in a laboratory. After five days, the egg is placed in the woman's womb.

With ICSI, an egg can be fertilized by a single sperm that otherwise would be unable to penetrate the zona pellucida (the permeable barrier around the egg) and bind to the egg. Once fertilization takes place, a couple's chance of giving birth to a single baby, twins, or triplets is the same if they have IVF with or without ICSI.

When is IVF with ICSI Used?

For the most part ICSI with IVF is used in cases of male factor infertility.

ICSI is offered to men:

  • Whose sperm has severe abnormalities
  • Whose sperm has failed to fertilize eggs in previous IVF cycles
  • Who have congenital or acquired absence or obstructions of the ejaculatory ducts
  • Who have had unsuccessful vasectomy reversals
  • With spinal cord injuries or pituitary deficiencies

ICSI is used to counter a female infertility factor when a woman produces:

  • A lower number of eggs
  • Low quality eggs
  • Both low quality and a low number

For more information about intracytoplasmic sperm injection (ICSI), please contact us.

ICSI is a method that has been used for many years and has helped many people achieve pregnancies. If male factor is a problem for you, then this may be a solution that you can look into.

Any questions about ICSI? Our fertility doctors at Reproductive Medicine Associates of Connecticut will be happy to answer!


About Lisa Rosenthal

Lisa has over thirty years of experience in the fertility field. After her personal infertility journey, she felt dissatisfied with the lack of comprehensive services available to support her. She was determined to help others undergoing fertility treatment. Lisa has been with RMACT for eleven years and serves as Patient Advocate and the Strategic Content Lead.

Lisa is the teacher and founder of Fertile Yoga, a program designed to support men and women on their quest for their families through gentle movement and meditation.

Lisa’s true passion is supporting patients getting into treatment, being able to stay in treatment and staying whole and complete throughout the process. Lisa is also a Certified Grief Recovery Specialist, which is helpful in her work with fertility patients.

Her experience also includes working with RESOLVE: The National Infertility Association and The American Fertility Association (now Path2Parenthood), where she was Educational Coordinator, Conference Director and Assistant Executive Director.